彭吉云 特聘研究员、博士生导师
研究方向：神经胶质细胞与脑的认知功能
主要荣誉及专业团队任职：省部级人才、中国神经科学学会神经胶质细胞分会委员。
邮箱：pengjy@ncu.edu.cn
主持课题项目：
1、国家自然科学基金项目：灵长类前额叶皮层在数量感知决策中的作用及其神经编码机制【批准号：32060199；起止时间：2021-2024】
代表性论文：
The voltage‑gated proton channel Hv1 promotes microglia‑astrocyte communication and neuropathic pain after peripheral nerve injury. Molecular Brain. 2021, 14(1):99. （第一&通讯作者）
Microglial Calcium: An Exquisite Sensor for Neuronal Activity. Neuroscience Bulletin. 2021, 37(6):582-584. （通讯作者）
Microglia and monocytes synergistically promote the transition from acute to chronic pain after nerve injury. Nature Communications. 2016, 7:12029. （第一作者）
Microglial P2Y12 receptor regulates ventral hippocampal CA1 neuronal excitability and innate fear in mice. Molecular Brain. 2019, 12:71. （第一作者）
Microglia Are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain. Cell Reports. 2019 Jun 25;27(13):3844-3859. （共同第一作者）
Pharmacological inactivation does not support a unique causal role for intraparietal sulcus in the discrimination of visual number. PLoS one. 2017, 12(12):e0188820.
Chemokine CCL2-CCR2 Signaling Induces Neuronal Cell Death via STAT3 Activation and IL-1β Production after Status Epilepticus. The Journal of Neuroscience. 2017, 37(33):7878-7892. （共同第一作者）
Spinal Microgliosis Due to Resident Microglial Proliferation Is Required for Pain Hypersensitivity after Peripheral Nerve Injury. Cell Reports. 2016, 16(3):605-14. （共同第一作者）
Protein synthesis is essential not only for consolidation but also for maintenance and post-retrieval reconsolidation of acrobatic motor skill in rats. Molecular Brain. 2009, 2:12. （第一作者）
Microglial P2Y12 receptors regulate seizure-induced neurogenesis and immature neuronal projections. The Journal of Neuroscience. 2019, Oct. 9 0487-19
Microglial proliferation and monocyte infiltration contribute to microgliosis following status epilepticus. Glia. 2019 Aug; 67(8):1434-1448
Dale B. Bosco, Jiaying Zheng, Zhiyan Xu, Jiyun Peng, Ukpong B. Eyo, Ke Tang, Cheng Yan, RNAseq analysis of hippocampal microglia after kainic acid-induced seizures. Mol Brain. 2018 Jun 20;11(1):34.
TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury. The Journal of Neuroscience 2017, 37(4):871-881.
Regulation of Physical Microglia-Neuron Interactions by Fractalkine Signaling after Status Epilepticus. eNeuro. 2017, 3(6).e0209-16.2016:1-14
Microglial P2Y12 receptors regulate microglial activation and surveillance during neuropathic pain. Brain, Behavior and Immunity. 2016, 55:82-92.
Neuronal Hyperactivity Recruits Microglial Processes via Neuronal NMDA Receptors and Microglial P2Y12 Receptors after Status Epilepticus. The Journal of Neuroscience. 2014, 34(32):10528-40
Neuronal representation of working memory in the medial prefrontal cortex of rats. Molecular Brain. 2014, 7:61
Methylphenidate enhances NMDA-receptor response in medial prefrontal cortex via sigma-1 receptor: a novel mechanism for methylphenidate action. PLoS One. 2012;7(12):e51910.
Selective deficit in no-go performance induced by blockade of prefrontal cortical alpha 2-adrenoceptors in monkeys. Neuroreport. 2003, 14(7):1013-6.